Soy Protein Containing Isoflavones Improves Facial Signs of Photoaging and Skin Hydration in Postmenopausal Women: Results of a Prospective Randomized Double-Blind Controlled Trial

Preliminary findings from multiple studies indicate that dietary intake of soy-derived isoflavones exert beneficial effects on the skin including defense against oxidant damage, stimulation collagen synthesis, and increased hydration. This study aims to investigate how oral supplementation a soy protein isolate with added (SPII) affects components photoaging such as facial wrinkles dyspigmentation, biophysical measures hydration sebum excretion in postmenopausal women. 6-month prospective, randomized double-blind controlled was conducted 44 women Fitzpatrick types I, II, III who were receive either casein or SPII. A high-resolution photography system used measure wrinkle severity pigmentation at 0, 8, 16, 24 weeks. Skin measurements included production. The average decreased SPII intervention group week 16 by 5.9% 7.1%, respectively, compared baseline. Compared group, significantly (p < 0.05) 0.0001). Facial pigment intensity −2.5% 24, whereas there no significant change group. baseline, 39% 68% left right cheeks 0.05), There differences Dietary may improve photoaging, increase III.